Thursday, January 8, 2015

Monitoring appointments 1 & 2

1/2: 10 units micro dose Lupron bid
1/3: 150 Follistim bid and 10 units micro dose Lupron bid
1/4: 150 Follistim bid and 10 units micro dose Lupron bid
1/5: 1 vial Menopur bid, 75 Follistim bid, and 10 units micro dose Lupron bid
1/6: 1 vial Menopur bid, 75 Follistim bid, and 10 units micro dose Lupron bid
First monitoring ultrasound: lining 2.5 (was just finishing my period), all follicles under 10 mm, ~30 on right, ~20 on left. Estrogen 411.
1/7: 1 vial Menopur bid, 75 Follistim bid, and 10 units micro dose Lupron bid + Humira in pm
1/8: 1 vial Menopur bid, 75 Follistim bid, and 10 units micro dose Lupron bid
Second monitoring ultrasound: lining 9, R ovary: 13, 12, 12, 11, 11, 10, many under 10, L ovary: 10, 10, 10, 10, several under 10. Estrogen 1338.

It looks like things are going well this round. I'm much happier with my estrogen. I think it might get pretty high by retrieval, but hopeful that will be in indication of many follicles, and many mature follicles. I am going to continue the same dose of meds and return for an ultrasound on Saturday. The follicles are still small but they all are growing, so hopefully it will be a nice, slow, steady increase. There is still time for those under 10 to catch up.

On Estrogen levels I've done a bit of reading, since I was worried with my low levels last cycle. From what I've read the goal is for Estrogen to reach 2000-4000 before retrieval (though I'm not sure if that is the level on day of trigger vs day of actual retrieval). Also there is a handy dandy equation that reflects expected Estrogen levels and number and size of follicles:

E2 = 291 pg/ml + 180 (x) + 64 (y) + 18.7 (z) 
where x, y and z represent follicles measuring >17 mm, 15 to 16 mm, and <14 mm respectively


I've also heard on average a mature follicle will produce ~200 pg/ml of estrogen. So far I'm just feeling a little uncomfortable in my lower abdomen already and had a little GI upset today. Otherwise, I'm feeling pretty happy and hopeful today.

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